
More than 5% for clearer blood sugar gains
- Published in
- J Acad Nutr Diet 2015
- People studied
- 6,754
In 11 trials with 6,754 adults with type 2 diabetes, clear gains in blood sugar, blood fats and blood pressure showed up in the programmes where people lost 5% or more.
- Checked against
- PubMed 25935570
- Published in
- J Acad Nutr Diet 2015
- Last checked
- 30 October 2026
Key takeaway
This pooled analysis of 11 randomised trials with 6,754 adults with type 2 diabetes and overweight or obesity looked at results after 12 months. Most programmes led to less than 5% weight loss, about 3 kg, and showed no clear change in HbA1c (long-term blood sugar), blood fats or blood pressure. The two programmes where people lost 5% or more, both with regular activity and frequent contact with health professionals, did show clear benefits.
At a glance
- Type of study
- pooled analysis of randomised trials (meta-analysis)
- People studied
- 6,754
- How long
- 12 months or more
- Compared with
- other weight-loss programmes or usual care
- Main result
- Clear benefits appeared with 5% or more lost, not with less.
- Strength of evidence
- Randomised trials
What this study does not show
Only two study groups reached 5% or more, so the comparison rests on few trials. The programmes that worked were intensive.
Results from studies in groups of people, mostly in diet and movement programmes. They cannot be promised to any one person. This information is educational and does not replace a consultation with a doctor.
More on metabolism
- Lower diabetes risk with each kiloLong-term or observational studies · Hamman et al., Diabetes Care 2006
- Better insulin responseSmall or uncontrolled studies · Magkos et al., Cell Metab 2016
- Half as many new diabetes casesRandomised trials · Tuomilehto et al., NEJM 2001
- More than 5% for clearer blood sugar gainsRandomised trials · Franz et al., J Acad Nutr Diet 2015
- More diabetes remission with fewer caloriesRandomised trials · Jayedi et al., Am J Clin Nutr 2023
- Remission of type 2 diabetes at 2 yearsRandomised trials · Lean et al., Lancet Diabetes Endocrinol 2019
- Fewer new cases of type 2 diabetesRandomised trials · Ruiz-Canela et al., Ann Intern Med 2025
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