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Randomised trialsBrain and mood

Fewer low moods on a lower-calorie diet

Published in
Adv Nutr 2024
People studied
2,040

Across 13 randomised trials in adults with conditions such as obesity, type 2 diabetes or high blood pressure, diet programmes went with a small drop in depression symptoms compared with control groups. The drop was a little larger with lower-calorie diets.

Checked against
PubMed 38184198
Published in
Adv Nutr 2024
Last checked
30 October 2026

Key takeaway

This pooled analysis looked at 13 randomised trials of diet programmes in adults with overweight, obesity, type 2 diabetes, high blood pressure or high cholesterol. On average, people on a diet programme had slightly fewer depression symptoms than control groups, and the effect was a little larger for lower-calorie diets. The diets showed no clear effect on anxiety.

At a glance

Type of study
pooled analysis of randomised trials (meta-analysis)
People studied
2,040
How long
1 month to 3 years
Compared with
control groups on their usual habits or given general diet advice
Main result
Small drop in depression symptoms, mainly on lower-calorie diets; no clear effect on anxiety.
Strength of evidence
Randomised trials

What this study does not show

The effect was small, and the trials differed a lot in diet, length and the people taking part. Not every trial was in people with overweight, and anxiety did not improve.

Results from studies in groups of people, mostly in diet and movement programmes. They cannot be promised to any one person. This information is educational and does not replace a consultation with a doctor.

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