a.clinicTalk to a doctor
Book a consultation
Randomised trialsBrain and mood

Sharper thinking in older age

Published in
Am J Clin Nutr 2014
People studied
107

In a one-year trial of 107 older adults with obesity and frailty, diet, exercise or both improved thinking test scores more than in the control group.

Checked against
PubMed 24787497
Published in
Am J Clin Nutr 2014
Last checked
30 October 2026

Key takeaway

107 older adults with obesity and frailty were randomly assigned to a weight-loss diet, exercise, both, or a control group for one year. Scores on a general thinking test and on weight-related quality of life improved more in all three programme groups than in the control group. Diet plus exercise improved more than diet alone, but not more than exercise alone.

At a glance

Type of study
randomised trial with four groups
People studied
107
How long
1 year
Compared with
a control group
Main result
Thinking scores and quality of life improved more than in the control group.
Strength of evidence
Randomised trials

What this study does not show

A small trial in older adults with frailty, and these results were not the trial's main question. Exercise alone did as well as diet plus exercise, so the gains are not down to weight loss alone, and mood scores did not change.

Results from studies in groups of people, mostly in diet and movement programmes. They cannot be promised to any one person. This information is educational and does not replace a consultation with a doctor.

The next step is a conversation, not a decision

A licensed doctor decides whether any treatment is right for you. The answer can also be no treatment.

  1. 1

    You fill in a short form

  2. 2

    We call you within 24 hours

  3. 3

    A paid 20-minute video consultation with a doctor

  4. 4

    The doctor goes through your options and decides what is right for you

Would you like to talk it through with a doctor?

Book a consultation